From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals. / Olsson, I. Anna S.; Nicol, Christine J.; Niemi, Steven M.; Sandøe, Peter.

In: ILAR Journal, 30.01.2020.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Olsson, IAS, Nicol, CJ, Niemi, SM & Sandøe, P 2020, 'From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals', ILAR Journal. https://doi.org/10.1093/ilar/ilz018

APA

Olsson, I. A. S., Nicol, C. J., Niemi, S. M., & Sandøe, P. (2020). From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals. ILAR Journal. https://doi.org/10.1093/ilar/ilz018

Vancouver

Olsson IAS, Nicol CJ, Niemi SM, Sandøe P. From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals. ILAR Journal. 2020 Jan 30. https://doi.org/10.1093/ilar/ilz018

Author

Olsson, I. Anna S. ; Nicol, Christine J. ; Niemi, Steven M. ; Sandøe, Peter. / From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals. In: ILAR Journal. 2020.

Bibtex

@article{50630740d7514b659927996b7a1b5545,
title = "From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals",
abstract = "The focus of this paper is the requirement that the use of live animals in experiments and in vivo assays should never be allowed if those uses involve severe suffering. This requirement was first implemented in Danish legislation, was later adopted by the European Union, and has had limited uptake in North America. Animal suffering can arise from exposure to a wide range of different external and internal events that threaten biological or social functions, while the severity of suffering may be influenced by the animals’ perceptions of their own situation and the degree of control they are able to exert. Severe suffering is more than an incremental increase in negative state(s) but involves a qualitative shift whereby the normal mechanisms to contain or keep negative states at arm’s length no longer function. The result of severe suffering will be a loss of the ability of cope. The idea of putting a cap on severe suffering may be justified from multiple ethical perspectives. In most, if not all, cases it is possible to avoid imposing severe suffering on animals during experiments without giving up the potential benefits of finding new ways to cure, prevent, or alleviate serious human diseases and generate other important knowledge. From this it follows that there is a strong ethical case to favor a regulatory ban on animal experiments involving severe suffering.",
author = "Olsson, {I. Anna S.} and Nicol, {Christine J.} and Niemi, {Steven M.} and Peter Sand{\o}e",
year = "2020",
month = "1",
day = "30",
doi = "10.1093/ilar/ilz018",
language = "English",
journal = "I L A R Journal",
issn = "1084-2020",
publisher = "Oxford University Press",

}

RIS

TY - JOUR

T1 - From unpleasant to unbearable: Why and how to implement an upper limit to pain and other forms of suffering in research with animals

AU - Olsson, I. Anna S.

AU - Nicol, Christine J.

AU - Niemi, Steven M.

AU - Sandøe, Peter

PY - 2020/1/30

Y1 - 2020/1/30

N2 - The focus of this paper is the requirement that the use of live animals in experiments and in vivo assays should never be allowed if those uses involve severe suffering. This requirement was first implemented in Danish legislation, was later adopted by the European Union, and has had limited uptake in North America. Animal suffering can arise from exposure to a wide range of different external and internal events that threaten biological or social functions, while the severity of suffering may be influenced by the animals’ perceptions of their own situation and the degree of control they are able to exert. Severe suffering is more than an incremental increase in negative state(s) but involves a qualitative shift whereby the normal mechanisms to contain or keep negative states at arm’s length no longer function. The result of severe suffering will be a loss of the ability of cope. The idea of putting a cap on severe suffering may be justified from multiple ethical perspectives. In most, if not all, cases it is possible to avoid imposing severe suffering on animals during experiments without giving up the potential benefits of finding new ways to cure, prevent, or alleviate serious human diseases and generate other important knowledge. From this it follows that there is a strong ethical case to favor a regulatory ban on animal experiments involving severe suffering.

AB - The focus of this paper is the requirement that the use of live animals in experiments and in vivo assays should never be allowed if those uses involve severe suffering. This requirement was first implemented in Danish legislation, was later adopted by the European Union, and has had limited uptake in North America. Animal suffering can arise from exposure to a wide range of different external and internal events that threaten biological or social functions, while the severity of suffering may be influenced by the animals’ perceptions of their own situation and the degree of control they are able to exert. Severe suffering is more than an incremental increase in negative state(s) but involves a qualitative shift whereby the normal mechanisms to contain or keep negative states at arm’s length no longer function. The result of severe suffering will be a loss of the ability of cope. The idea of putting a cap on severe suffering may be justified from multiple ethical perspectives. In most, if not all, cases it is possible to avoid imposing severe suffering on animals during experiments without giving up the potential benefits of finding new ways to cure, prevent, or alleviate serious human diseases and generate other important knowledge. From this it follows that there is a strong ethical case to favor a regulatory ban on animal experiments involving severe suffering.

U2 - 10.1093/ilar/ilz018

DO - 10.1093/ilar/ilz018

M3 - Journal article

C2 - 31996924

JO - I L A R Journal

JF - I L A R Journal

SN - 1084-2020

ER -

ID: 240787874