Protein supplementation combined with low-intensity resistance training in geriatric medical patients during and after hospitalization: A randomized, double-blind, multicenter trial

Research output: Contribution to journalJournal articlepeer-review

  • Josephine Gade
  • Anne Marie Beck
  • Hanne Elkjær Andersen
  • Britt Christensen
  • Rønholt, Finn
  • Tobias W Klausen
  • Anders Vinther
  • Arne Astrup

Sarcopenia (loss of muscle mass/strength) burdens many older adults - hospitalized older adults being particularly vulnerable. Treating the condition, protein-supplementation (PrS) and resistance-training (RT) may act synergistically. Therefore, this block-randomised, double-blind, multicentre intervention study, recruiting geriatric patients >70 years from three Medical Departments, investigated the effect of PrS combined with RT during hospitalization and 12 weeks after discharge. Participants were randomly allocated (1:1) to receive PrS (totally 27.5 g whey protein/day, ≈2000 kJ/day) or iso-energetic placebo-products (0.05). In conclusion, PrS increasing total protein intake by 0.4 and 0.2 g/kg/d during hospitalization and after discharge, respectively, does not seem to increase the adaptive response to low intensity/volume RT in geriatric medical patients.

Original languageEnglish
JournalBritish Journal of Nutrition
Volume122
Issue number9
Pages (from-to)1006-1020
Number of pages15
ISSN0007-1145
DOIs
Publication statusPublished - 2019

    Research areas

  • Faculty of Science - Sarcopenia, Older adults, Acutely ill, Milk-based, Resistance exercise training, Muscle strength, Muscle mass, Physical function, Rehabilitation

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