Painful dilemmas: the ethics of animal-based pain research
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Painful dilemmas: the ethics of animal-based pain research. / Magalhães-Sant'Ana, M.; Sandøe, Peter; Olsson, I. A. S.
In: Animal Welfare, Vol. 18, No. 1, 2009, p. 49-63.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Painful dilemmas: the ethics of animal-based pain research
AU - Magalhães-Sant'Ana, M.
AU - Sandøe, Peter
AU - Olsson, I. A. S.
PY - 2009
Y1 - 2009
N2 - While it has the potential to deliver important human benefits, animal-based pain research raises ethical questions, because it involves inducing pain in sentient beings. Ethical decision-making, connected with this variety of research, requires informed harm-benefit analysis, and the aim of this paper is to provide information for such an analysis. We present an overview of the different models and their consequences for animal welfare, showing that, of the many animal models available, most have a considerable welfare impact on the animal. While the usual approach to pain control through administration of analgesic substances is usually unsuitable in pain research, refinement remains an option, both within the experimental protocol and in general husbandry and handling.Drawing on the overview, we develop a discussion of the ethical acceptability of animal-based pain research against the background of the kinds of harm done to the animals involved, the potential for refinement, and the expected benefits of the research.
AB - While it has the potential to deliver important human benefits, animal-based pain research raises ethical questions, because it involves inducing pain in sentient beings. Ethical decision-making, connected with this variety of research, requires informed harm-benefit analysis, and the aim of this paper is to provide information for such an analysis. We present an overview of the different models and their consequences for animal welfare, showing that, of the many animal models available, most have a considerable welfare impact on the animal. While the usual approach to pain control through administration of analgesic substances is usually unsuitable in pain research, refinement remains an option, both within the experimental protocol and in general husbandry and handling.Drawing on the overview, we develop a discussion of the ethical acceptability of animal-based pain research against the background of the kinds of harm done to the animals involved, the potential for refinement, and the expected benefits of the research.
M3 - Journal article
VL - 18
SP - 49
EP - 63
JO - Animal Welfare
JF - Animal Welfare
SN - 0962-7286
IS - 1
ER -
ID: 10093400