Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia

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Standard

Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia. / Bang, D.; Emborg, J.; Elkjaer, J.; Benfield, T.L.; Lundgren, Jens.

I: Respiratory Medicine, Bind 95, Nr. 8, 2001, s. 661-665.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Bang, D, Emborg, J, Elkjaer, J, Benfield, TL & Lundgren, J 2001, 'Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia', Respiratory Medicine, bind 95, nr. 8, s. 661-665. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11530954&query_hl=24>

APA

Bang, D., Emborg, J., Elkjaer, J., Benfield, T. L., & Lundgren, J. (2001). Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia. Respiratory Medicine, 95(8), 661-665. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11530954&query_hl=24

Vancouver

Bang D, Emborg J, Elkjaer J, Benfield TL, Lundgren J. Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia. Respiratory Medicine. 2001;95(8):661-665.

Author

Bang, D. ; Emborg, J. ; Elkjaer, J. ; Benfield, T.L. ; Lundgren, Jens. / Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia. I: Respiratory Medicine. 2001 ; Bind 95, Nr. 8. s. 661-665.

Bibtex

@article{c7b6d070f39011ddbf70000ea68e967b,
title = "Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia",
abstract = "The use of mechanical ventilation (MV) for AIDS-related Pneumocystis carinii pneumonia (PCP) has varied over time. The introduction of adjunctive corticosteroid therapy has changed the pathophysiology of PCP. In the present study, we attempted to identify factors predictive of severe respiratory failure requiring MV amongst patients with PCP treated in the era of adjunctive corticosteroid therapy. Furthermore, we studied factors associated with survival in relation to MV. Of 170 consecutive patients with AIDS-related PCP, 18 (11%) required MV. Thirteen of 18 ventilated patients died (72%). In a logistic regression analysis, higher age, increased bronchoalveolar lavage (BAL) neutrophilia and a positive BAL cytomegalovirus CMV culture were associated with the need of MV. In multivariate analyses, only BAL neutrophilia remained independently predictive of mechanical ventilation. In conclusion, short-term mortality remained high after the introduction of adjunctive corticosteroid therapy. BAL neutrophilia may be a useful prognostic marker to identify patients at high risk of requiring mechanical ventilation Udgivelsesdato: 2001/8",
author = "D. Bang and J. Emborg and J. Elkjaer and T.L. Benfield and Jens Lundgren",
note = "DA - 20010903IS - 0954-6111 (Print)LA - engPT - Journal ArticleSB - IM",
year = "2001",
language = "English",
volume = "95",
pages = "661--665",
journal = "Respiratory Medicine",
issn = "0954-6111",
publisher = "Elsevier",
number = "8",

}

RIS

TY - JOUR

T1 - Independent risk of mechanical ventilation for AIDS-related Pneumocystis carinii pneumonia associated with bronchoalveolar lavage neutrophilia

AU - Bang, D.

AU - Emborg, J.

AU - Elkjaer, J.

AU - Benfield, T.L.

AU - Lundgren, Jens

N1 - DA - 20010903IS - 0954-6111 (Print)LA - engPT - Journal ArticleSB - IM

PY - 2001

Y1 - 2001

N2 - The use of mechanical ventilation (MV) for AIDS-related Pneumocystis carinii pneumonia (PCP) has varied over time. The introduction of adjunctive corticosteroid therapy has changed the pathophysiology of PCP. In the present study, we attempted to identify factors predictive of severe respiratory failure requiring MV amongst patients with PCP treated in the era of adjunctive corticosteroid therapy. Furthermore, we studied factors associated with survival in relation to MV. Of 170 consecutive patients with AIDS-related PCP, 18 (11%) required MV. Thirteen of 18 ventilated patients died (72%). In a logistic regression analysis, higher age, increased bronchoalveolar lavage (BAL) neutrophilia and a positive BAL cytomegalovirus CMV culture were associated with the need of MV. In multivariate analyses, only BAL neutrophilia remained independently predictive of mechanical ventilation. In conclusion, short-term mortality remained high after the introduction of adjunctive corticosteroid therapy. BAL neutrophilia may be a useful prognostic marker to identify patients at high risk of requiring mechanical ventilation Udgivelsesdato: 2001/8

AB - The use of mechanical ventilation (MV) for AIDS-related Pneumocystis carinii pneumonia (PCP) has varied over time. The introduction of adjunctive corticosteroid therapy has changed the pathophysiology of PCP. In the present study, we attempted to identify factors predictive of severe respiratory failure requiring MV amongst patients with PCP treated in the era of adjunctive corticosteroid therapy. Furthermore, we studied factors associated with survival in relation to MV. Of 170 consecutive patients with AIDS-related PCP, 18 (11%) required MV. Thirteen of 18 ventilated patients died (72%). In a logistic regression analysis, higher age, increased bronchoalveolar lavage (BAL) neutrophilia and a positive BAL cytomegalovirus CMV culture were associated with the need of MV. In multivariate analyses, only BAL neutrophilia remained independently predictive of mechanical ventilation. In conclusion, short-term mortality remained high after the introduction of adjunctive corticosteroid therapy. BAL neutrophilia may be a useful prognostic marker to identify patients at high risk of requiring mechanical ventilation Udgivelsesdato: 2001/8

M3 - Journal article

VL - 95

SP - 661

EP - 665

JO - Respiratory Medicine

JF - Respiratory Medicine

SN - 0954-6111

IS - 8

ER -

ID: 10156664