Dietary protein requirements and recommendations for healthy older adults: a critical narrative review of the scientific evidence
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Dietary protein requirements and recommendations for healthy older adults: a critical narrative review of the scientific evidence. / Nishimura, Yusuke; Højfeldt, Grith; Breen, Leigh; Tetens, Inge; Holm, Lars.
In: Nutrition Research Reviews, Vol. 36, No. 1, 2023, p. 69-85.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Dietary protein requirements and recommendations for healthy older adults: a critical narrative review of the scientific evidence
AU - Nishimura, Yusuke
AU - Højfeldt, Grith
AU - Breen, Leigh
AU - Tetens, Inge
AU - Holm, Lars
N1 - A correction to this publication has been published at: https://doi.org/10.1017/S0954422421000408
PY - 2023
Y1 - 2023
N2 - Adequate protein intake is essential for the maintenance of whole-body protein mass. Different methodological approaches are used to substantiate the evidence for the current protein recommendation, and it is continuously debated whether older adults require more protein to counteract the age-dependent loss of muscle mass, sarcopenia. Thus, the purpose of this critical narrative review is to outline and discuss differences in the approaches and methodologies assessing the protein requirements and hence, resulting in controversies in current protein recommendations for healthy older adults. Through a literature search, this narrative review first summarizes the historical development of the FAO/WHO/UNU setting of protein requirements and recommendations for healthy older adults. Hereafter, we describe the various types of studies (epidemiological studies and protein turnover kinetic measurements) and applied methodological approaches founding the basis and the different recommendations with focus on healthy older adults. Finally, we discuss important factors to be considered in future studies to create evidence for international agreement on protein requirements and recommendations for healthy older adults. We conclude by proposing future directions to determine "true" protein requirement and recommendation for healthy older adults.
AB - Adequate protein intake is essential for the maintenance of whole-body protein mass. Different methodological approaches are used to substantiate the evidence for the current protein recommendation, and it is continuously debated whether older adults require more protein to counteract the age-dependent loss of muscle mass, sarcopenia. Thus, the purpose of this critical narrative review is to outline and discuss differences in the approaches and methodologies assessing the protein requirements and hence, resulting in controversies in current protein recommendations for healthy older adults. Through a literature search, this narrative review first summarizes the historical development of the FAO/WHO/UNU setting of protein requirements and recommendations for healthy older adults. Hereafter, we describe the various types of studies (epidemiological studies and protein turnover kinetic measurements) and applied methodological approaches founding the basis and the different recommendations with focus on healthy older adults. Finally, we discuss important factors to be considered in future studies to create evidence for international agreement on protein requirements and recommendations for healthy older adults. We conclude by proposing future directions to determine "true" protein requirement and recommendation for healthy older adults.
KW - Faculty of Science
KW - Ageing
KW - Sarcopenia
KW - Amino acid
KW - Protein synthesis
KW - Protein breakdown
KW - Net protein balance
KW - Protein turnover
KW - Metabolic adaptation
KW - Energy balance
KW - Protein intake
U2 - 10.1017/S0954422421000329
DO - 10.1017/S0954422421000329
M3 - Review
C2 - 34666855
VL - 36
SP - 69
EP - 85
JO - Nutrition Research Reviews
JF - Nutrition Research Reviews
SN - 0954-4224
IS - 1
ER -
ID: 282472813